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Tom gets a cut on his hand.After several days he notes swelling,pain,heat,and redness.Upon opening the wound to relieve the pressure,the presence of pus is noted.What has happened to the wound?

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The wound has become infected,probably w...

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Which statement is true about T cells?


A) They will develop into cytotoxic T cells if antigen is complexed with class II MHC proteins.
B) Once activated,they cannot secrete cytokines.
C) Their proliferation is enhanced by interleukins 1 and 2.
D) They usually directly recognize antigens,which then activates a subpopulation of killer cells.

E) None of the above
F) A) and C)

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The antibody that becomes bound to mast cells and basophils and causes the cells to release histamine and other chemicals is ________.

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The directional movement of cells in response to chemicals is called chemotaxis.

A) True
B) False

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B lymphocytes develop immunocompetence in the ________.


A) bone marrow
B) lymph nodes
C) thymus
D) spleen

E) B) and D)
F) A) and B)

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The primary immune response ________.


A) has a lag period while B cells proliferate and differentiate into plasma cells
B) is another name for immunological memory
C) occurs more rapidly and is stronger than the secondary response
D) occurs when memory cells are stimulated

E) None of the above
F) All of the above

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Fever ________.


A) production is regulated by chemicals that reset the body's thermostat to a higher setting
B) decreases the metabolic rate of the body to conserve energy
C) is a higher-than-normal body temperature that is always dangerous
D) causes the liver to release large amounts of iron,which seems to inhibit bacterial replication

E) C) and D)
F) B) and D)

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Plasma cells ________.


A) have a great deal of rough endoplasmic reticulum reflecting the fact that they secrete a tremendous amount of protein (antibody)
B) are small so that they slip between endothelial cells of capillaries to fight infection in the surrounding tissues
C) have a great deal of rough endoplasmic reticulum to dispose of ingested pathogens
D) are large so that they can envelope their prey by phagocytosis

E) B) and D)
F) C) and D)

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Which of the following does not describe actions of interferon (IFN) ?


A) IFN binds to normal,uninfected cells stimulating the activation of genes that produce anti-viral proteins.
B) IFN can penetrate the viral capsid and destroy the virus.
C) Virally infected cells can release interferon which attracts NK cells to attack and kill the IFN secreting cell.
D) IFN will attract macrophages to the secreting cell to be removed by phagocytosis.

E) A) and D)
F) A) and C)

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Cancer cells and virus-infected body cells can be killed before activation of adaptive immunity by ________.


A) B lymphocytes
B) T lymphocytes
C) pinocytosis
D) natural killer cells

E) A) and B)
F) C) and D)

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Select the best description of the negative selection process of lymphocyte maturation.


A) removal of lymphocytes that fail to recognize "self" cells
B) teaching a lymphocyte to recognize "self" from foreign antigens
C) removal of lymphocytes that react with "self" cells
D) allowing the survival of lymphocytes that cannot bind to MHC proteins

E) None of the above
F) B) and D)

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An advantage of innate immunity is ________.


A) its barriers that prevent pathogens from entering into the body
B) the use of antibodies to cause cell lysis and kill invading cells
C) the numerous steps in the activation of its cells that can prevent autoimmune disease
D) the specificity of its individual cells which specialize in the removal on one type of antigen

E) None of the above
F) All of the above

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Pure antibody preparations specific for a single antigenic determinant are called ________ antibodies.

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Which of the following best describes the qualities of most antigens?


A) macromolecules that are produced by the host organism
B) atomic elements that are not normally present in the human body
C) macromolecules that are foreign to the host
D) atomic elements that are harmful or toxic

E) B) and D)
F) B) and C)

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Phagocyte mobilization involves ________.


A) monocytes as the most active phagocyte
B) diapedesis,during which cells line up against the capillary wall
C) mainly neutrophil and macrophage migration into inflamed areas
D) margination,which is the process of white cell movement through the walls of capillaries into injured tissues

E) A) and B)
F) A) and C)

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Fever is often a beneficial immune response because it can speed the activities of leucocytes.

A) True
B) False

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Which of the following is not a complement activation pathway?


A) lectin pathway
B) alternative pathway
C) lactate pathway
D) classical pathway

E) B) and C)
F) A) and D)

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A flu vaccine is needed seasonally to be effective but a polio vaccine is only needed once.The best explanation of this is ________.


A) the flu vaccine is substantially weaker than the polio vaccine
B) exposure to flu vaccine produces no memory cells from proliferating B-lymphocytes
C) the polio virus is substantially weaker than the flu virus
D) the flu has several strains that change seasonally

E) B) and C)
F) None of the above

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Natural killer (NK) cells ________.


A) can kill cancer cells before the immune system is activated
B) are also called cytotoxic T cells
C) are cells of the adaptive immune system
D) are a type of phagocyte

E) All of the above
F) B) and C)

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The most common type of immediate hypersensitivity is ________.

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