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A viroid is a completely developed infectious agent composed of nucleic acid and surrounded by a capsid.

A) True
B) False

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The following steps occur during multiplication of retroviruses. Which is the fourth step?


A) penetration
B) uncoating
C) attachment
D) synthesis of double-stranded DNA
E) synthesis of +RNA

F) None of the above
G) B) and C)

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D

The mechanism whereby an enveloped virus leaves a host cell is called


A) budding.
B) transduction.
C) penetration.
D) abduction.
E) lysogeny.

F) D) and E)
G) C) and D)

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The basic mechanism of viral multiplication is similar for all viruses.

A) True
B) False

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An example of a latent viral infection is


A) cold sores.
B) mumps.
C) subacute sclerosing panencephalitis.
D) smallpox.
E) influenza.

F) B) and E)
G) A) and C)

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Which of the following is NOT used as a criterion to classify viruses?


A) morphology
B) size
C) number of capsomeres
D) biochemical tests
E) nucleic acid

F) C) and D)
G) B) and D)

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A segmented genome can result in antigenic shift.

A) True
B) False

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Which of the following is most likely a product of an early gene?


A) envelope proteins
B) spike proteins
C) capsid proteins
D) DNA polymerase
E) lysozyme

F) A) and D)
G) A) and C)

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Binomial nomenclature is used to name viruses.

A) True
B) False

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A viral species is a group of viruses that


A) has the same genetic information and ecological niche.
B) has the same morphology and nucleic acid.
C) infects the same cells and cause the same disease.
D) cannot be defined.

E) None of the above
F) A) and C)

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Most drugs that interfere with viral multiplication also interfere with host cell function.

A) True
B) False

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Discuss why viruses are considered infectious ʺparticlesʺ on the borderline between living and non-living.

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not answered

The definition of lysogeny is


A) the period during replication when virions are not present.
B) when the burst time takes an unusually long time.
C) attachment of a phage to a cell.
D) lysis of the host cell due to a phage.
E) phage DNA is incorporated into host cell DNA.

F) B) and C)
G) A) and E)

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Bacteriophages derive all of the following from the host cell EXCEPT


A) tRNA.
B) lysozyme.
C) nucleotides.
D) amino acids.
E) ATP.

F) B) and D)
G) C) and D)

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B

Figure 13.2 Figure 13.2    -Assume a patient had chickenpox (human herpesvirus 3)  as a child. Which line on the graph in Figure 13.2 would show the number of viruses present in this person as a 60 -year-old with shingles (human herpesvirus 3) ? A)  a B)  b C)  c D)  d E)  e -Assume a patient had chickenpox (human herpesvirus 3) as a child. Which line on the graph in Figure 13.2 would show the number of viruses present in this person as a 60 -year-old with shingles (human herpesvirus 3) ?


A) a
B) b
C) c
D) d
E) e

F) None of the above
G) B) and C)

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The following steps occur during biosynthesis of a + strand RNA virus. What is the third step?


A) synthesis of viral proteins
B) synthesis of + strand RNA
C) penetration and uncoating
D) synthesis of - strand RNA
E) attachment

F) A) and D)
G) B) and E)

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Figure 13.1 Figure 13.1    -In Figure 13.1, which structure is a complex virus? A)  a B)  b C)  c D)  d E)  All of the structures are complex viruses. -In Figure 13.1, which structure is a complex virus?


A) a
B) b
C) c
D) d
E) All of the structures are complex viruses.

F) B) and E)
G) C) and E)

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Continuous cell lines differ from primary cell lines in that


A) continuous cell lines always have to be re-isolated from animal tissues.
B) continuous cell lines are derived from primary cell lines.
C) viruses can be grown in continuous cell lines.
D) continuous cell lines are from human embryos.
E) continuous cell lines can be maintained through an indefinite number of generations.

F) None of the above
G) A) and C)

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Which of the following statements is FALSE?


A) A prophage is phage DNA inserted into a bacterial chromosome.
B) A prophage may result in new properties of the host cell.
C) Prophage genes are repressed by a repressor protein coded for by the prophage.
D) A prophage can ʺpopʺ out of the chromosome.
E) The prophage makes the host cell immune to infection by other phages.

F) All of the above
G) A) and C)

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Which of the following places these items in the correct order for DNA-virus replication? 1. Maturation 2) DNA synthesis 3) Transcription 4) Translation


A) 2; 3; 4; 1
B) 4; 3; 2; 1
C) 3; 4; 1; 2
D) 4; 1; 2; 3
E) 1; 2; 3; 4

F) D) and E)
G) B) and D)

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