Question 1

Clonal selection requires the presence of foreign antigens.

Accepted Answer

A) True 
 B)False

Question 2

_____ is the most abundant class of antibodies in serum.

Accepted Answer

A)  IgG
B)  IgM
C)  IgA
D)  IgD
E)  IgEF) A) and D)
G) A) and B)

Question 3

The structural and functional differences that distinguish immunoglobulin isotypes are due to variations associated with their Fc fragments.

Accepted Answer

A) True 
 B)False

Question 4

Vaccinia virus is often used in the technique to make

Accepted Answer

A)  adjuvant.
B)  booster.
C)  antibodies to toxin.
D)  gamma globulin.
E)  "Trojan horse" recombinant vaccine.F) A) and B)
G) B) and D)

Question 5

The molecular fragment on an antigen molecule that a lymphocyte recognizes and responds to is called a/an

Accepted Answer

A)  epitope.
B)  hapten.
C)  antigen binding site.
D)  variable region.E) A) and D)
F) A) and C)

Question 6

Antigen presenting cells

Accepted Answer

A)  include dendritic cells.
B)  include macrophages.
C)  engulf and modify antigen to be more immunogenic.
D)  hold and present processed antigen on their cell membrane surface.
E)  All of the choices are correct.F) A) and D)
G) All of the above

Question 7

The immunoglobulin class that has an Fc region that binds to receptors on basophils and mast cells is

Accepted Answer

A)  IgA.
B)  IgD.
C)  IgE.
D)  IgG.
E)  IgM.F) B) and D)
G) B) and E)

Question 8

Which process involves antibodies cross-linking cells or particles into large aggregates?

Accepted Answer

A)  neutralization
B)  opsonization
C)  complement fixation
D)  agglutination
E)  anamnestic responseF) All of the above
G) None of the above

Question 9

Live,attenuated vaccines

Accepted Answer

A)  include the Sabin polio vaccine.
B)  include the measles,mumps,rubella vaccine (MMR) .
C)  contain viable microbes that can multiply in the person.
D)  require smaller doses and fewer boosters compared to inactivated vaccines.
E)  All of the choices are correct.F) B) and D)
G) A) and B)

Question 10

During presentation of APC-bound antigen,macrophages and dendritic cells secrete the cytokine _____,which activates T helper cells.

Accepted Answer

A)  interferon
B)  interleukin-1
C)  interleukin-2
D)  histamineE) A) and B)
F) A) and C)

Question 11

Antibody molecules circulate in lymph,blood,and tissue fluids.

Accepted Answer

A) True 
 B)False

Question 12

Which process involves antibodies coating microorganisms in order to facilitate phagocytosis?

Accepted Answer

A)  neutralization
B)  opsonization
C)  complement fixation
D)  agglutination
E)  anamnestic responseF) B) and E)
G) A) and B)

Question 13

Lymphocytes

Accepted Answer

A)  possess MHC antigens for recognizing self.
B)  have membrane receptors that recognize foreign antigens.
C)  gain tolerance to self by destruction of lymphocytes that could react against self.
D)  develop into clones of B and T cells with extreme variations of specificity.
E)  All of the choices are correct.F) A) and E)
G) B) and C)

Question 14

After secreting antibodies during an immune response,plasma cells then differentiate into memory cells.

Accepted Answer

A) True 
 B)False

Question 15

Gamma globulin can be given as immunotherapy to confer artificial passive immunity.

Accepted Answer

A) True 
 B)False

Question 16

An example of artificial passive immunity would be

Accepted Answer

A)  chickenpox infection,followed by lifelong immunity.
B)  chickenpox vaccine triggering extended immunity to chickenpox.
C)  giving a person immune serum globulins to chickenpox virus after exposure to the disease.
D)  a fetus acquiring maternal IgG to the chickenpox virus across the placenta.E) B) and D)
F) None of the above

Question 17

Which of the following is not true of the antigen-independent period of lymphocyte development?

Accepted Answer

A)  Lymphocytes form from stem cells in the bone marrow.
B)  Random genetic rearrangements occur to produce different surface protein receptors.
C)  Mature lymphocytes populate lymphatic organs and encounter antigens.
D)  Lymphocytes with specificity for self are destroyed.
E)  Many lymphocytes with different specificities are formed.F) B) and C)
G) A) and C)

Question 18

Which process involves a more rapid synthesis and greatly increased titer of antibody when the immune system is subsequently exposed to the same antigen?

Accepted Answer

A)  neutralization
B)  opsonization
C)  complement fixation
D)  agglutination
E)  anamnestic responseF) C) and D)
G) A) and B)

Question 19

Killed or inactivated vaccines are prepared by

Accepted Answer

A)  removal of virulence genes from the microbe.
B)  treatment with formalin,heat,or radiation.
C)  passage of the pathogen through unnatural hosts or tissue culture.
D)  long-term subculturing of the microbe.E) None of the above
F) All of the above

Question 20

The immunoglobulin class that has a dimer form found in mucus,saliva,colostrum,and other body secretions is

Accepted Answer

A)  IgA.
B)  IgD.
C)  IgE.
D)  IgG.
E)  IgM.F) B) and C)
G) All of the above

Exam 15: Host Defenses II: Specific Immunity and Immunization

Antigen presenting cells

Correct AnswerverifiedShow Answer

The immunoglobulin class that has an Fc region that binds to receptors on basophils and mast cells is

Correct AnswerverifiedShow Answer

Killed or inactivated vaccines are prepared by

Correct AnswerverifiedShow Answer

Which process involves antibodies coating microorganisms in order to facilitate phagocytosis?

Correct AnswerverifiedShow Answer

Clonal selection requires the presence of foreign antigens.

Correct AnswerverifiedShow Answer

Which process involves antibodies cross-linking cells or particles into large aggregates?

Correct AnswerverifiedShow Answer

Antibody molecules circulate in lymph,blood,and tissue fluids.

Correct AnswerverifiedShow Answer

The structural and functional differences that distinguish immunoglobulin isotypes are due to variations associated with their Fc fragments.

Correct AnswerverifiedShow Answer

Which process involves a more rapid synthesis and greatly increased titer of antibody when the immune system is subsequently exposed to the same antigen?

Correct AnswerverifiedShow Answer

Which of the following is not true of the antigen-independent period of lymphocyte development?

Correct AnswerverifiedShow Answer

During presentation of APC-bound antigen,macrophages and dendritic cells secrete the cytokine _____,which activates T helper cells.

Correct AnswerverifiedShow Answer

An example of artificial passive immunity would be

Correct AnswerverifiedShow Answer

The immunoglobulin class that has a dimer form found in mucus,saliva,colostrum,and other body secretions is

Correct AnswerverifiedShow Answer

The molecular fragment on an antigen molecule that a lymphocyte recognizes and responds to is called a/an

Correct AnswerverifiedShow Answer

After secreting antibodies during an immune response,plasma cells then differentiate into memory cells.

Correct AnswerverifiedShow Answer

Gamma globulin can be given as immunotherapy to confer artificial passive immunity.

Correct AnswerverifiedShow Answer

Vaccinia virus is often used in the technique to make

Correct AnswerverifiedShow Answer

_____ is the most abundant class of antibodies in serum.

Correct AnswerverifiedShow Answer

Lymphocytes

Correct AnswerverifiedShow Answer

Live,attenuated vaccines

Correct AnswerverifiedShow Answer

Correct Answer
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