Question 1

The use of ______ to treat stimulant dependence via action on the GABAergic system has been limited by drug-induced loss of peripheral vision.

Accepted Answer

A)  baclofen (Lioresal) 
B)  lamotrigine (Lamictal) 
C)  gamma-vinyl-GABA (Vigabatrin) 
D)  valproateE) A) and C)
F) B) and D)

Question 2

As opposed to crack cocaine,a "line" of powder cocaine:

Accepted Answer

A)  acts on different receptors in the brain.
B)  acts at different sites in the brain.
C)  has a more rapid speed of onset.
D)  typically yields about 1/10th to 1/40th the dose.E) A) and B)
F) All of the above

Question 3

The effects of __________ are indistinguishable from those of cocaine.

Accepted Answer

A)  anxiolytics
B)  sedatives
C)  hallucinogens
D)  amphetaminesE) B) and C)
F) A) and C)

Question 4

Because the cocaine __________,the drug poorly crosses the mucosal membrane.

Accepted Answer

A)  is water-soluble in its hydrochloride form
B)  molecules are too small to pass through mucosal membranes
C)  is a potent vasodilator
D)  is a potent vasoconstrictorE) A) and B)
F) A) and C)

Question 5

Sigmund Freud encouraged the use of cocaine to treat:

Accepted Answer

A)  anxiety
B)  panic attacks
C)  bipolar disorder
D)  depressionE) B) and D)
F) A) and D)

Question 6

The positive reinforcing effects of cocaine are most likely the result of action on the neurotransmitter:

Accepted Answer

A)  norepinephrine.
B)  dopamine.
C)  serotonin.
D)  acetylcholine.E) All of the above
F) C) and D)

Question 7

Brain imaging studies suggest that the commonly abused dose of cocaine blocks:

Accepted Answer

A)  only about 20 percent of dopamine transporters.
B)  about 30 percent of dopamine transporters.
C)  more than 60 percent of dopamine transporters.
D)  virtually all dopamine receptors in the brain.E) All of the above
F) B) and D)

Question 8

MDPV (methylenedioxypyrovalerone) is _____ potent than cocaine.

Accepted Answer

A)  2 to 5 times less
B)  2 to 5 times more
C)  10 to 50 times less
D)  10 to 50 times moreE) A) and B)
F) All of the above

Question 9

Which of the following administration routes for cocaine has the FASTEST initial onset of action?

Accepted Answer

A)  The oral route
B)  By smoking cocaine
C)  The intranasal route
D)  The intravenous routeE) A) and B)
F) A) and C)

Question 10

Dependence on cocaine can produce _____ brain damage of _____.

Accepted Answer

A)  localized; white matter
B)  localized; gray matter
C)  widespread; white matter
D)  widespread; gray matterE) None of the above
F) All of the above

Question 11

With the street name "__________," is the smokable crystalline form of methamphetamine.

Accepted Answer

A)  ice
B)  crack
C)  crank
D)  crystalE) A) and B)
F) B) and D)

Question 12

The unique ester of benzoylecgonine is produced when enzymes in the:

Accepted Answer

A)  liver metabolize cocaine.
B)  liver metabolize ethyl alcohol.
C)  plasma metabolize cocaine.
D)  liver metabolize cocaine and ethyl alcohol.E) A) and B)
F) All of the above

Question 13

Because it is __________,cocaine hydrochloride does not cross mucus membranes well.

Accepted Answer

A)  cocaethanol
B)  ethylcocaine
C)  cocaoethylene
D)  cocaethyleneE) B) and D)
F) A) and D)

Question 14

Cocaethylene is a very potent blocker of _____ channels in the heart.

Accepted Answer

A)  sodium
B)  potassium
C)  calcium
D)  chlorideE) A) and D)
F) B) and D)

Question 15

Cocaine base,or "freebase," is _____ soluble.

Accepted Answer

A)  water
B)  lipid
C)  both water and lipid
D)  neither water or lipidE) B) and D)
F) A) and D)

Question 16

"Ice" is to methamphetamine as ____ is to ____.

Accepted Answer

A)  cocaine; amphetamine
B)  cocaine; "crack"
C)  "ice"; "crack"
D)  "crack"; cocaineE) A) and D)
F) B) and C)

Question 17

Amphetamine abuse declined in the 1960s and 1970s.Which of the following statements is NOT one of the reasons?

Accepted Answer

A)  Drug companies decreased production of the drug.
B)  Users recognized that compulsive amphetamine use was dangerous.
C)  The focus on treating depression with amphetamine declined because better antidepressants were introduced.
D)  A new street drug,a smokable form of amphetamine called "ice," became popular.E) C) and D)
F) All of the above

Exam 7: Cocaine,the Amphetamines,and Other Psychostimulants

The use of ______ to treat stimulant dependence via action on the GABAergic system has been limited by drug-induced loss of peripheral vision.

Correct Answer
verified

"Ice" is to methamphetamine as is to .

Correct Answer
verified

Brain imaging studies suggest that the commonly abused dose of cocaine blocks:

Correct Answer
verified

Because the cocaine __________,the drug poorly crosses the mucosal membrane.

Correct Answer
verified

Which of the following administration routes for cocaine has the FASTEST initial onset of action?

Correct Answer
verified

The positive reinforcing effects of cocaine are most likely the result of action on the neurotransmitter:

Correct Answer
verified

Because it is __________,cocaine hydrochloride does not cross mucus membranes well.

Correct Answer
verified

The unique ester of benzoylecgonine is produced when enzymes in the:

Correct Answer
verified

Sigmund Freud encouraged the use of cocaine to treat:

Correct Answer
verified

Cocaine base,or "freebase," is _____ soluble.

Correct Answer
verified

The effects of __________ are indistinguishable from those of cocaine.

Correct Answer
verified

Cocaethylene is a very potent blocker of _____ channels in the heart.

Correct Answer
verified

MDPV (methylenedioxypyrovalerone) is _____ potent than cocaine.

Correct Answer
verified

As opposed to crack cocaine,a "line" of powder cocaine:

Correct Answer
verified

Dependence on cocaine can produce _ brain damage of _.

Correct Answer
verified

Amphetamine abuse declined in the 1960s and 1970s.Which of the following statements is NOT one of the reasons?

Correct Answer
verified

With the street name "__________," is the smokable crystalline form of methamphetamine.

Correct Answer
verified

Exam 7: Cocaine,the Amphetamines,and Other Psychostimulants

The use of ______ to treat stimulant dependence via action on the GABAergic system has been limited by drug-induced loss of peripheral vision.

Correct AnswerverifiedShow Answer

"Ice" is to methamphetamine as ____ is to ____.

Correct AnswerverifiedShow Answer

Brain imaging studies suggest that the commonly abused dose of cocaine blocks:

Correct AnswerverifiedShow Answer

Because the cocaine __________,the drug poorly crosses the mucosal membrane.

Correct AnswerverifiedShow Answer

Which of the following administration routes for cocaine has the FASTEST initial onset of action?

Correct AnswerverifiedShow Answer

The positive reinforcing effects of cocaine are most likely the result of action on the neurotransmitter:

Correct AnswerverifiedShow Answer

Because it is __________,cocaine hydrochloride does not cross mucus membranes well.

Correct AnswerverifiedShow Answer

The unique ester of benzoylecgonine is produced when enzymes in the:

Correct AnswerverifiedShow Answer

Sigmund Freud encouraged the use of cocaine to treat:

Correct AnswerverifiedShow Answer

Cocaine base,or "freebase," is _____ soluble.

Correct AnswerverifiedShow Answer

The effects of __________ are indistinguishable from those of cocaine.

Correct AnswerverifiedShow Answer

Cocaethylene is a very potent blocker of _____ channels in the heart.

Correct AnswerverifiedShow Answer

MDPV (methylenedioxypyrovalerone) is _____ potent than cocaine.

Correct AnswerverifiedShow Answer

As opposed to crack cocaine,a "line" of powder cocaine:

Correct AnswerverifiedShow Answer

Dependence on cocaine can produce _____ brain damage of _____.

Correct AnswerverifiedShow Answer

Amphetamine abuse declined in the 1960s and 1970s.Which of the following statements is NOT one of the reasons?

Correct AnswerverifiedShow Answer

With the street name "__________," is the smokable crystalline form of methamphetamine.

Correct AnswerverifiedShow Answer

Correct Answer
verified

"Ice" is to methamphetamine as is to .

Correct Answer
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Dependence on cocaine can produce _ brain damage of _.

Correct Answer
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Correct Answer
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